What causes such distress that dying doesn’t seem unreasonable? That’s one of the more frustrating things about migraines-headache experts aren’t quite sure.

The main symptom of migraine is a severe headache, often accompanied by nausea or vomiting. A migraine can last from four hours to three days. The disorder generally starts around puberty and diminishes by middle age. Migraines are often related to menstrual periods or to specific foods. The condition affects more women than men.